AUTOIMMUNE · INFLAMMATORY ARTHRITIS

Rheumatoid Arthritis diagnosis & treatment in Bhubaneswar

Rheumatoid arthritis is an autoimmune disease in which the immune system attacks the lining of your joints, causing pain, swelling and morning stiffness.

Medically reviewed by Dr. Jyoti Ranjan Parida, MD, DM (Rheumatology)Updated July 2026
OVERVIEW

What is rheumatoid arthritis?
an autoimmune joint disease

Rheumatoid arthritis (RA) is an autoimmune disease in which there is inflammation of the joint synovium — the lining of the joints — because of an immune attack.

  • It usually affects small and large joints of both the upper and lower limbs.
  • Due to inflammation, there is pain, swelling and difficulty in movement of the joints.
  • Symptoms become more prominent in the morning hours, after getting up from bed.
  • Patients usually have difficulty in holding objects, raising the hand and performing day-to-day activities.
Illustration of a patient with inflamed, swollen joints caused by rheumatoid arthritis
Illustration: how rheumatoid arthritis inflames the joint lining.
SYMPTOMS

Signs & symptoms
what RA feels like

  • Usually RA presents with pain, swelling and stiffness of the small joints of the hand after getting up from bed.
  • A person suffering from RA may have difficulty in making a fist of the hand, combing the hair, opening a water bottle, brushing the teeth, getting up from the chair etc.
  • RA can affect any joints of the body — starting from the cervical spine, shoulder, wrist and small joints of the hand to the knee, ankle and small joints of the foot. Usually it doesn’t affect the lower back and terminal finger joints.
  • Many a times it causes joint deformity, making the patient bedbound.
  • Apart from the joints, it can affect other body parts like the lungs, causing dry cough and breathlessness, the eyes (red eye), skin nodules etc.
  • If not treated in time, it may increase the risk of heart attack.
Video thumbnail: Dr. Jyoti Ranjan Parida of OARC Bhubaneswar explains rheumatoid arthritis symptoms

Watch: Dr. Parida explains rheumatoid arthritis symptoms (opens YouTube)

Morning stiffness lasting more than 30 minutes? See a rheumatologist early — with proper treatment from an early stage, the joint deformity RA causes can be prevented.

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CAUSES

What causes
rheumatoid arthritis?

  • Rheumatoid arthritis is an autoimmune disease in which there is inflammation of the joint synovium because of an immune attack.
  • Normally our immune system attacks outside invading organisms like bacteria and viruses, and is designed to protect our own body parts, like the joints.
  • In rheumatoid arthritis, the immune system becomes dysregulated and attacks one’s own joints. Although it is not completely known why this happens, there is a contribution of multiple factors such as genes, environment, infection etc.
  • Smoking and poor dental hygiene (gingivitis) are known to trigger the autoimmune process in some patients having rheumatoid arthritis.
Video thumbnail: Dr. Jyoti Ranjan Parida discusses primary reasons behind arthritis — OARC

Watch: Primary reasons behind arthritis — Dr. Jyoti Ranjan Parida (opens YouTube)

FAST FACTS

Rheumatoid arthritis
at a glance

1 in 100
RA affects around 1 per cent of the world’s population — out of 100 people, one is likely to have this disease.
3 : 1
Women to men — for every 3 women affected by RA, one man experiences the same.
25–50
RA most commonly affects women of child-bearing age, between 25 and 50 years.
Normal life
With proper treatment, one can have a normal lifestyle in rheumatoid arthritis.

Although some genetic factors are responsible for RA, it doesn’t usually run in families.

Rheumatologists are the specialists who are trained to treat this disease.

DIAGNOSIS

How rheumatoid arthritis
is diagnosed

RA is mainly diagnosed by a trained rheumatologist — it should never be diagnosed on a blood test alone.

Clinical examination

RA is mainly diagnosed by a trained rheumatologist or physician by taking a complete symptom history and a good clinical examination. RA should not be diagnosed only based upon a blood test.

Blood tests: RF & anti-CCP

Rheumatoid factor and anti-CCP antibody tests help in making the diagnosis — with proper rheumatology consultation. Some normal healthy persons have these antibodies in low quantity without the disease, while one-third of RA patients have negative blood tests yet suffer from RA (seronegative rheumatoid arthritis).

Imaging: X-ray / MRI

Radiological tests like X-ray are helpful only in detecting long-term joint damage. In doubtful cases, the physician may ask for an MRI of the joints, which picks up disease inflammation at an early stage. Usually these tests are not required.

Monitoring panel

Some blood tests are ordered to monitor the effects of prescribed drugs. These include Complete Blood Count (CBC), C-Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR), Liver Function Test (LFT) and Kidney Function Test.

Video thumbnail: Dr. Jyoti Ranjan Parida explains what is rheumatoid arthritis — OARC Bhubaneswar

Watch: What is Rheumatoid Arthritis — Dr. Jyoti Ranjan Parida (opens YouTube)

TREATMENT

How rheumatoid arthritis
is treated

Short-term relief

You may be prescribed painkillers (NSAIDs) and low-dose steroid medications at disease onset for pain relief — but usually they are given only for short periods.

DMARDs — the main treatment

The drugs that are useful in treating RA are known as DMARDs (Disease Modifying Antirheumatic Drugs). They include Methotrexate, Sulfasalazine, Hydroxychloroquine, Leflunomide etc. If taken properly under supervision, these drugs help to control joint inflammation and give the patient a normal life.

Supervision & monitoring

These drugs should be prescribed and taken under the supervision of a rheumatologist, as they are trained to periodically monitor your blood tests to look for any side effects of these drugs.

Biologic drugs

Biological drugs are new drugs that target specific molecules like TNF and other cytokines which incite inflammation in RA. They are very effective drugs but, because of high costs, are usually given after failure of other drugs. Biologic drugs that are effective in RA include Etanercept, Adalimumab, Infliximab, Golimumab, Rituximab, Tocilizumab, Abatacept etc.

Our Treat-to-Target approach

RA care at OARC works towards a target agreed with you from the first visit — remission, or low disease activity where that is more realistic. At each review, your disease activity is measured with the DAS28 score, built from an examination of your joints, your blood inflammation markers and your own rating of how you are doing. That score, rather than guesswork, guides every decision: active disease prompts a step-up in treatment, while sustained remission may allow a careful, supervised step-down of medicines.

Review visits with the OARC rheumatology team run Monday to Saturday, 9:00 AM–2:00 PM and 4:30–9:00 PM. Call +91 93386 53086 or book online.

How OARC Can Help?

At OARC, we offer holistic care to patients suffering from all kinds of arthritis and autoimmune diseases by our renowned rheumatologists. Because of the chronic nature of the disease, we spend time with the patient helping them to know about their disease, and demystify the myths regarding the disease and treatment. We have collaboration with an NABL accredited laboratory where all kinds of blood tests can be done at reasonable costs. We also have a patient support system which patients can approach in case of any emergency. We believe in a friendly relation with patients so that they can share all their sufferings and get the best possible treatment.

  • Best doctors to treat
  • State-of-the-art clinic
  • All facilities available under one roof
  • NABL accredited laboratory
  • Same-day test results
  • Convenient location
Video thumbnail: Dr. Jyoti Ranjan Parida explains how to treat rheumatoid arthritis — MBCTv OARC

Watch: How to treat Rheumatoid Arthritis — Prof. Dr. Jyoti Ranjan Parida (opens YouTube)

OUTLOOK

What happens if RA
is left untreated?

  • With proper treatment, a rheumatoid arthritis patient can lead a normal life without pain and deformity.
  • But if not treated properly from an early stage, there may be severe joint deformity and crippling.
  • It may increase the risk of heart attack.
  • It may involve other organs — the lungs causing interstitial lung disease, the eyes causing scleritis, the nerves causing neuropathy etc.

Questions to ask your doctor

  • Which DMARD is right for me, and how long before it starts working?
  • How often will my blood tests be monitored while on treatment?
  • What side effects should I watch for, and when should I call the clinic?
  • Can I exercise and continue my day-to-day activities?
  • What are my chances of remission and a normal life with treatment?
FAQ

Frequently Asked Questions
arthritis care in Odisha

With proper treatment, a rheumatoid arthritis patient can lead a normal life without pain and deformity. But if not treated properly from an early stage, there may be severe joint deformity and crippling. Rheumatologists are the specialists trained to treat this disease.
Although some genetic factors are responsible for RA, it doesn’t usually run in families. Multiple factors contribute — genes, environment and infection. Smoking and poor dental hygiene (gingivitis) are known to trigger the autoimmune process in some patients.
Rheumatoid factor (RF) and anti-CCP antibody tests help in making the diagnosis, but RA should not be diagnosed based on a blood test alone. Some normal healthy persons can have these antibodies in low quantity without having the disease, while about one-third of RA patients have negative blood test results yet still suffer from RA (seronegative rheumatoid arthritis). Tests such as CBC, CRP, ESR, liver and kidney function tests are used to monitor treatment.
Biological drugs are new drugs that target specific molecules like TNF and other cytokines which incite inflammation in RA. They are very effective but, because of high costs, are usually given after failure of other drugs. Biologics effective in RA include Etanercept, Adalimumab, Infliximab, Golimumab, Rituximab, Tocilizumab and Abatacept.
Yes — remission, or low disease activity, is the goal of modern RA treatment. With DMARDs taken regularly under a rheumatologist’s supervision, joint pain and swelling can settle and day-to-day life can return to normal. Treatment usually continues even when you feel well; any reduction in medicines should only happen gradually, under specialist supervision, once remission is sustained.
Usually for the long term — RA is a chronic condition, and DMARDs are continued for years rather than weeks, because stopping early commonly lets joint inflammation return. Your rheumatologist will monitor your blood tests periodically for side effects and adjust doses as the disease settles. Never stop or change your medicines on your own; raise any concerns at your review visit.
Both cause painful, swollen joints, but for different reasons. RA is an autoimmune disease in which the immune system inflames the joint lining, typically affecting the small joints of both hands with morning stiffness. Gout is caused by uric acid crystals and tends to strike suddenly, often in a single joint. The treatments are entirely different, so accurate diagnosis matters — learn more about gout treatment in Bhubaneswar.
YOUR SPECIALIST

Meet the rheumatologist
behind your care

Dr. Jyoti Ranjan Parida, Founder and Lead Rheumatologist at OARC Bhubaneswar
Founder & Lead Rheumatologist

Dr. Jyoti Ranjan Parida

MBBS · MD · DM (Rheumatology) · Gold Medallist · UK Fellowship

Founder & Lead Rheumatologist at OARC. Dr. Parida pioneered specialist rheumatology care in Odisha since 2014 and leads the OARC rheumatology team — with fellow rheumatologist Dr. Debashis Maikap — at our Bhubaneswar centre. Consultations run Monday to Saturday, 9:00 AM–2:00 PM and 4:30–9:00 PM.

Areas of expertise
Rheumatoid ArthritisLupusAnkylosing SpondylitisGout
4.7 / 5 · Over 2,000 patient reviews on JustDial & Practo
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Media Appearances

Video thumbnail: My Doctor — Rheumatoid Arthritis, Dr. Jyoti Ranjan Parida, Etv News Odia — OARC

Watch: Dr. Parida on Etv News Odia — Rheumatoid Arthritis (opens YouTube)

Meet the Full Team
RELATED CONDITIONS

If you are also experiencing sudden joint pain or high uric acid levels, you may be suffering from gout — a related but distinct condition. Learn more about gout treatment in Bhubaneswar from our rheumatology team.

Gout

Sudden, severe joint pain with high uric acid levels — a related but distinct condition, treated by our rheumatology team.

Learn More
Psoriatic Arthritis

Inflammatory arthritis that occurs in some people with psoriasis, affecting joints and skin.

Learn More
Ankylosing Spondylitis

Inflammatory arthritis that mainly affects the spine and lower back, typically in young adults.

Learn More
Osteoarthritis

Wear-and-tear arthritis — stiffness usually eases within minutes and pain worsens with activity, unlike RA.

Learn More
Medical disclaimer: This page is for general information about rheumatoid arthritis and does not replace personal medical advice, diagnosis or treatment from a qualified rheumatologist. Please consult a doctor for advice about your own condition. References: American College of Rheumatology (patient education on rheumatoid arthritis); Arthritis Foundation (rheumatoid arthritis resources).

Early treatment prevents joint damage.

Consult Odisha’s dedicated arthritis & rheumatology centre — Mon–Sat, 9:00 AM–2:00 PM & 4:30–9:00 PM, Saheed Nagar, Bhubaneswar.