Sjogren’s syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. Sjögren’s syndrome is an autoimmune condition that can occur at any age, but is most common in older women. Many patients develop Sjögren’s syndrome as a complication of another autoimmune disease, such as rheumatoid arthritis or lupus. Complications in other parts of the body can occur. Pain and stiffness in the joints with mild swelling may occur in some patients, even in those without rheumatoid arthritis or lupus. Rashes on the arms and legs related to inflammation in small blood vessels (vasculitis) and inflammation in the lungs, liver, and kidney may occur rarely and be difficult to diagnose.