Our body’s immune system is an amazing network of cells that function from very simple to highly complex levels. The purpose of this system is to protect us from our environment and look out for any damage in our own cells. However, sometimes the system goes awry and wild. It misreads signals. As a result our defenses do not recognises our body at work and “begin” attacking “ cells. This leads to illness called autoimmune( self-immune) diseases and one of such disease is “Systemic Lupus Erythematosus” commonly known as “Lupus”, which is an inflammatory disease of connective tissue. It mainly effects females in the age group of 15 – 45 years. It is very difficult to diagnose. It is not a single disease. It can affect one’s skin, joints, scalp and might also leads to hair loss. We need to identify whether it is a mild variety or severe requiring aggressive treatment.