1. What happens if serum uric acid increases ? Q&A › Category: Questions › 1. What happens if serum uric acid increases ? 0 Vote Up Vote Down Supriya asked 1 year ago 1 Answers 0 Vote Up Vote Down OARC Staff answered 1 year ago If serum uric acid increase beyond 6 or 7, it may cause a type of arthritis cause Gout. Sometimes it can cause kidney stones or renal failure if increase for prolong period. so better to consult a rheumatologist if you have high uric acid level.